郑健茂
副主任医师 硕士生导师
导师简介

学位 / 学历

博士 / 博士研究生

学术简历

2006-2011 中山大学口腔医学专业获学士学位

2011-2016 中山大学口腔医学专业获博士学位

研究方向

1.牙体牙髓病

2.牙髓组织再生

3.压电材料-口腔组织再生的交叉学科研究

主持课题

1. 2022-2024年《外泌体miR-758-3p靶向调控PTEN/PI3K/Akt通路调控巨噬细胞M2极化促进SHED成牙本质向分化》,广东省自然科学基金面上项目,10万

2. 2022 -2024年《外泌体miR-200c-3p靶向调控PTEN/PI3K/Akt通路调控巨噬细胞M2极化促进SHED成牙本质向分化》,广东省医学科研基金项目,0.5万

3. 2019-2022年《外泌体miR-27a-5p靶向调控LTBP1/TGF-β1通路促进DPSC成牙本质向分化的机制研究》,广东省自然科学基金面上项目,10万

4. 2018-2020年《MagT1激活Hspa12a/MAPK信号通路诱导BMMSCs成牙本质向分化的作用机制研究》,国家自然科学基金青年项目,20万

5. 2017-2019年《MagTl介导Hspa12a激活MAPK信号通路诱导骨髓间充质干细胞成牙本质向分化的机制研究》,中山大学青年教师培育项目,15万

发表论文

1.Jianmao Zheng*, Jiyuan Zuo, Cairong Xiao, Qining Guo, Xiaobin Fu,  Chengyun Ning, Peng Yu**, Wireless electrical stimulation generated by piezoelectric nanomaterial promotes the dental pulp regeneration via regulating mitochondrial Ca2+/PKA signaling pathway,journal of material science & technology, 2024, 168:24-34 (1区,IF=11.2)

2.Ziyu Zhou; Jianmao Zheng*; Danle Lin; Ruoman Xu; Yanan Chen; Xiaoli Hu ; Exosomes derived from dental pulp stem cells accelerate cutaneous wound healing by enhancing angiogenesis via the Cdc42/p38 MAPK pathway, International Journal of Molecular Medicine, 2022, 50(6): 143(3区,IF=5.7)

3.Jianmao Zheng; Yuanyuan Kong; Xiaoli Hu; Zhishan Li; Yaoyin Li1;Yingqun Zhong; Xi Wei; Junqi Ling; MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis., Stem Cell Research & Therapy, 2020, 11(1): 517. (2区,IF=7.1)

4.Zheng JM, Kong YY, Li YY, Zhang W. MagT1 regulated the odontogenic differentiation of BMMSCs induced byTGC-CM via ERK signaling pathway. Stem Cell Res Ther. 2019;10(1):48. (2区,IF=7.1)

5. Yuanyuan Kong; Xiaoli Hu; Yingqun Zhong; Ke Xu; Buling Wu*; Jianmao Zheng*; Magnesium-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells by activating ERK/BMP2/Smads signaling, Stem Cell Research & Therapy, 2019, 10(1): 378. (2区,IF=7.1)

6.Hu XL, Zhong YQ, Kong YY, Chen YN, Feng JM, Zheng JM*. Lineage-specific exosomes promote the odontogenic differentiation of dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of mircoRNAs. Stem Cell Res Ther.2019;10:170. (2区,IF=7.1)

7. Haozhen Ma, Jianmao Zheng*, Xiaolan Li,Potential risk of certain cancers among patients with Periodontitis: a supplementary meta-analysis of a large-scale population,Int J Med Sci. 2020 Sep 12;17(16):2531-2543. (3区,IF:3.2)

8. Yanan Chen,Jianmao Zheng#,Danna Li,Zhuwei Huang,Zijing Huang,Xue Wang,Xiaolei Zhang,Xiaoli Hu,Three-dimensional position of mandibular third molars and its association with distal caries in mandibular second molars: a cone beam computed tomographic study,Clinical Oral Investigations (2020) 24:3265–3273(2区,IF:3.1)

参编教材与论著

1. 2024年 参编《牙体牙髓病学多学科诊疗病例精粹》 人民卫生出版社

2. 2024年 参编《牙体牙髓病临床治疗新技术》 科学技术文献出版社  

获奖及学术荣誉

1. 2022 广东省柯麟医学教育基金会优秀教师奖

2. 2020 中山大学光华口腔医学院优秀教师奖二等奖

3. 2022 中山大学光华园丁奖二等奖

社会兼职

1. 广东省口腔医学会牙体牙髓专委会委员

2. 广州市青年医师协会委员

3. International journal of oral science审稿人

4. Stem cell research & therapy审稿人

联系方式

地址:广州市陵园西路56号

邮箱:547353439@qq.com