赵川江
博士生导师
硕士生导师
导师简介
【学位 / 学历】
博士 / 博士研究生
【学术简历】
1993.09-2000.06 华西医科大学口腔医学专业获硕士学位
2000.09-2003.06 四川大学口腔医学专业获博士学位
2019.12-2020.12 美国加州大学旧金山分校牙周病学访问学者
【研究方向】
1. 牙周微生物致病机制
2. 牙周炎免疫微环境调控机制
3. 牙周炎治疗体系研发
【主持课题】
1. 2024-2027年：《NETs通过激活STAT3-OPA1通路调控T细胞糖代谢重编程促进Th17细胞分化的机制研究》，国家自然科学基金面上项目，48万
2. 2019-2022年：《牙龈卟啉单胞菌脂多糖通过JMJD3-STAT3调控Th17细胞分化的机制研究》，国家自然科学基金面上项目，57万
【发表论文】
1. Yao J# , Zhang C# , Yu C#, Wu Li , Tan L, Li W*, Gao L*, Zhao C*. Immune Microenvironment Modulation for Treating Inflammatory Periodontal Bone Defects Using a Dynamic Dual-Responsive Hydrogel. Journal of Materials Chemistry B, 2025, DOI: 10.1039/D5TB00784D.
2. Zhang Y#, Ren J#, Shen Z #, Yang J, Lin Z , Shi X* , Zhao C*, Xia J *. BMP2 peptide-modified polycaprolactone-collagen nanosheets for periodontal tissue regeneration. Frontiers in Bioengineering and Biotechnology. 2025 Mar 5:13:1523735.
3.Tan L#, Zhang C#, Kou X, Zhao L, Wu D, Li J, Yu C, Xu T, Gao L, Mao X*, Zhao C *. Apoptotic Vesicles Attenuate Acute Lung Injury via CD73-Mediated Inhibition of Platelet Activation and NETosis. International Journal of Nanomedicine. 2025, 20: 91-107.
4.Ding J#, Tan L#, Wu L#, Li J; Zhang Y, Shen Z, Zhang C, Zhao C*, Gao L*. Regulation of Tryptophan-Indolemetabolic Pathway in Porphyromonas Gingivalis Virulence and Microbiota Dysbiosis in Periodontitis. NPJ Biofilms Microbiomes. 2025, 11(1): 37.
5. Zhang C#, Tan L#, Li J , Shen Z, Yao J, Huang Y, Wu L, Yu C , Gao L*, Zhao C*. REV-ERBα Inhibits Osteoclastogenesis and Protects Against Alveolar Bone Loss. Journal of Dental Research. 2024, Dec 4:220345241290444.
6. Ding J#, Li J#, Zhang C, Tan L, Zhao C*, Gao L*. High-Throughput Combined Analysis of Saliva Microbiota and Metabolomic Profile in Chinese Periodontitis Patients: A Pilot Study. Inflammation.2024,47(3):874-890.
7. Wu S#, Gao L#, Fu J, Zhao C*, Wang P*. The Application of Virtual Simulation Technology in Scaling and Root Planing Teaching. International Dental Journal. 2024 ,74(2):303-309.
8. Wang P#, Gao L, Ning Y, Zheng Y, Zhang C, Tan L, Zhao C*. Implementation of Chief Complaint-Based Clinical Reasoning Training in Periodontal Internships. International Dental Journal. 2024, S0020-6539(24)01531-4.
9. Fu J#, Lao Z, Gao L, Wu S, Huang X, Zhao C*, Wang P*. Effectiveness of typodont, quail egg and virtual simulation for ultrasonic periodontal scaling teaching among pre-clinical students: a randomized trial. BMC Oral Health. 2024, 24(1):86.
10. Wang P#, Wu S#, Gao L, Ning Y, Zhang C, Pan S, Zhao C*. The effect of virtual simulation technology applied to undergraduate teaching of periodontal probing. European Journal of Dental Education. 2024, 28(2):461-470.
11. Wu L#, Li X#, Li J, Wang Y, Yang C , Zhao C*, Gao L*. The role of aryl hydrocarbon receptor in the occurrence and development of periodontitis. Frontiers in Immunology. 2024,15:1494570.
12. Zhao C#, Kuraji R, Ye C, Gao L, Radaic A, Kamarajan P, Taketani Y, Kapila YL*. Nisin a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer's disease-like neuroinflammation triggered by periodontal disease. Journal of Neuroinflammation. 2023, 20(1):228.
13. Ding J#, Zhao C*, Gao L*. Ding J. Metabolism of periodontal pathobionts: Their regulatory roles in the dysbiotic microbiota. Molecular Oral Microbiology. 2023,38(3):181-188.
14. Huang Y#, Zhang L#, Tan L, Zhang C, Li X, Wang P, Gao L*, Zhao C*. Interleukin-22 Inhibits Apoptosis of Gingival Epithelial Cells Through TGF-β Signaling Pathway During Periodontitis. Inflammation. 2023, 46(5):1871-1886.
15. Zhang C#, Ren L#, Zhang H, Yang S, Deng M, He L, Cao R, Zhao C*, Xia J *. SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3. Human Cell. 2022, 35(4):1100-1113.14.
16.Huang D#, Zhang C, Wang P, Li X, Gao L*, Zhao C*. JMJD3 Promotes Porphyromonas gingivalis Lipopolysaccharide-Induced Th17-Cell Differentiation by Modulating the STAT3-RORc Signaling Pathway. DNA and cell biology. 2022,41(8):778-787.
17. Wang P#, Gao L, Li G, Zhao C*. Human β-defensin 2 enhances IL-1β production and pyroptosis through P2X7-mediated NLRP3 expression in macrophages. Biocell. 2022 ,46(5): 1197-1207.17.
18. Zhang C#, Xu C, Gao L, Li X, Zhao C*. Porphyromonas gingivalis lipopolysaccharide promotes T-helper 17 cell differentiation by upregulating Delta-like ligand 4 expression on CD14+ monocytes. Peer J. 2021 9:e11094.
19. Zhao C#, Chen Q, Yu S, Xu C, Li X, Zhang C, Gao L*. Effect of interleukin-22 on osteogenic differentiation and the osteoclastogenic response of human periodontal ligament fibroblasts in vitro. Journal of Periodontology. 2020,91(8):1085-1097.
20.彭焱#，张驰，高雳，李希庭，赵川江*.IV期牙周炎患者的正畸考量和时机选择.口腔医学. 2025, 45(1):25-36.19.
21. 张驰#，张璐，任俊贤，李金雨，谭灵屏，高雳，赵川江*.白细胞介素-22通过调节菌群和E-钙黏蛋白表达保护牙龈上皮屏障的研究.中华口腔医学杂志. 2024, 59(7): 653-662.
【参编教材与论著】
1.2023年 主编《光动力疗法的原理及其在口腔疾病治疗中的应用》 中国人口出版社 9787510194634
2.2024年 参编《口腔科学》 人民卫生出版社 9787117362375
3.2025年 参编《牙周病学》 人民卫生出版社
【获奖及学术荣誉】
2024年 美国牙周病学会卓越临床研究奖
【社会兼职】
1. 中华口腔医学会牙周病学专业委员会 副主任委员
2. 广东省口腔医学会牙周病学专业委员会主任委员
3. 中国医院协会口腔医院分会常委
4. 中华口腔医学研究杂志（电子版）编委
5. 牙体牙髓牙周病学杂志编委
【联系方式】
地址：广东省广州市陵园西路56号中山大学附属口腔医院牙周病科
