【学位 / 学历】

博士 / 博士研究生

【学术简历】

2004.09-2009.06 中山大学口腔医学专业获学士学位

2009.09-2014.06 中山大学口腔临床医学（硕博连读）专业获博士学位

2023.05-2024.04 新加坡国立神经科学研究所神经科学访问学者

【研究方向】

1.牙髓细胞生物学

2.根尖周组织免疫调节机制

【主持课题】

2023年：《HMGB1调控缺氧诱导人牙髓细胞线粒体自噬和铁死亡交互作用的机制研究》，广东省自然科学基金-青年提升项目，30万

【发表论文】

1. Lv Xiaomin, Cuiting Luo, Jie Wu, Yihua Huang, Jingjing Quan, Qimei Gong*, Zhongchun Tong*. Intergration of single-cell RNA sequencing of endothelial cells and proteomics to unravel the role of ICAM1-PTGS2 communication in apical periodontitis: A laboratory investigation. Int Endod J. 2024 Sep;57(9):12228-1246

2. Qimei Gong, Xiaomin Lv, Chenxi Liao, Ailin Liang, Cuiting Luo, Jie Wu, Yanling Zhou, Yihua Huang*, Zhongchun Tong*. Single-cell RNA sequencing combined with proteomics of infected macrophages reveals prothymosin-α as a target for treatment of apoical periodontitis. J Adv Res. 2024 Dec:66:349-361

3.Baoyu Li, Ailin Liang, Yanling Zhou, Yihua Huang, Chenxi Liao, Xufang Zhang*, Qimei Gong*. Hypoxia preconditioned DPSC-derived exosomes regulate angiogenesis via transferring LOXL2. Exp Cell Res. 2023 Apr 15;425(2):113543

4.Ainlin Liang, Luo Huang, Baoyu Li, Yihua Huang, Xiaoyan Zhou, Xufang Zhang, Qimei Gong. Micro-CT Evaluation of Different Root Canal Irrigation Protocols on the Removal of Accumulated Hard Tissue Debris: A Systematic Review and Meta-Analysis. J Clin Med. 2022 Oct 13;11(20):6053

5. Shaofeng An, Yanhuo Chen, Ting Yang, Yihua Huang, Yiwei Liu. A role for the calcium-sensing receptor in the expression of inflammatory mediators in LPS-treated human dental pulp cells. Mol Cell Biochem. 2022 Dec;477(12):2871-2881.

6. Yiwen Liu#, Liuchi Chen#, Qimei Gong, Hongwei Jiang*, Yihua Huang*. Hypoxia-induced mitophagy regulates proliferation, migration and odontoblastic differentiation of human dental pulp cells through FUN14 domain-containing 1. Int J Mol Med. 2022 May;49(5):72

7. Cheng Xu, Yu Du, Jun Tian, Chang Liu, Yihua Huang, Ti Zhou, Yang Ning. Pigment epithelium-derived factor modulates periodontal homeostasis in mice and induces osteogenic differentiation of human periodontal ligament fibroblasts. Connect Tissue Res. 2022 Sep;63(5):485-497.

8. Yihua Huang, Xuyan Li, Yiwen Liu, Qimei Gong, Jun Tian, Hongwei Jiang. LPS-induced autophagy in human dental pulp cells is associated with p38. J Mol Histol. 2021 Oct;52(5):919-928

【社会兼职】

1. 广东省牙体牙髓专委会青年委员

【联系方式】

地址：广州市越秀区陵园西路58号中山大学附属口腔医院

电话：83861544

邮箱：huangyh48@mail.sysu.edu.cn