【学位 / 学历】

博士 / 博士研究生

【学术简历】

2003.09- 2010.08 武汉大学口腔医学七年制专业获学士、硕士学位

2010.10-2014.09 日本九州大学小儿齿科专业获博士学位

2018.10-2019.03 美国宾夕法尼亚大学牙学院访问学者

【研究方向】

1.间充质干细胞

2.细胞外囊泡

3.组织再生

【主持课题】

2018.01-2020.12：《JHDM1d调控ERK信号通路在牙髓干细胞成骨分化及骨修复过程中的作用研究》，国家自然科学基金青年项目，20万

【发表论文】

1．Lai H#, Lin L#, Pan Y, Wang B, Ma L*, Zhao W*. Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Improve 5-FU-Induced Delayed Wound Healing by Mitochondrial Transfer. Pharmaceutics. 2025 Apr 1;17(4):453. (3区，IF:4.9)

2．Ma L, Chen C, Liu D, Huang Z, Li J, Liu H, Kin Kwok RT, Tang B, Sui B, Zhang X, Tang J, Mao X, Huang W, Shi S*, Kou X*. Apoptotic extracellular vesicles are metabolized regulators nurturing the skin and hair. Bioact Mater. 2023,1:626-641. (1区，IF:18)

3．Ma L#, Huang Z#, Wu D, Kou X, Mao X, Shi S*. CD146 controls the quality of clinical grade mesenchymal stem cells from human dental pulp. Stem Cell Res Ther. 2021;12(1):488. (2区，IF:7.1)

4．Lai H#, Li J#, Kou X, Mao X, Zhao W*, Ma L*. Extracellular Vesicles for Dental Pulp and Periodontal Regeneration. Pharmaceutics. 2023;14;15(1):282. (3区，IF:4.9)

5．Zhao L#, Zhu L#, Yang D#, Xie H, Ma L. Evaluation of complications in patients with mandible fractures undergoing chronic kidney disease in the United States. BMC Oral Health. 2024 Sep 19;24(1):1116. (2区，IF:2.6)

6．Sui B, Wang R, Chen C, Kou X, Wu D, Fu Y, Lei F, Wang Y, Liu Y, Chen X, Xu H, Liu Y, Kang J, Liu H, Kin Kwok RT, Tang BZ, Yan H, Wang M, Xiang L, Yan X, Zhang X, Ma L, Shi S*, Jin Y*. Apoptotic Vesicular Metabolism Contributes to Organelle Assembly and Safeguards Liver Homeostasis and Regeneration. Gastroenterology. 2024 Feb 9: S0016-5085(24)00136-7. (1区，IF:26.3)

7．Jiang Y#, Hao M#, Jiang F, Li J, Yang K, Li C, Ma L, Liu S, Kou X, Shi S*, Ding X*, Zhang X*, Tang J*. Lyophilized apoptotic vesicle-encapsulated adhesive hydrogel sponge as a rapid hemostat for traumatic hemorrhage in coagulopathy. J Nanobiotechnology. 2023 Nov 3;21(1):407.（1区，IF:10.6）

10.Zhang X#, Tang J#, Kou X, Huang W, Zhu Y, Jiang Y, Yang K, Li C, Hao M, Qu Y, Ma L, Chen C, Shi S*, Zhou Y*. Proteomic analysis of MSC-derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions. J Extracell Vesicles. 2022;11(7):e12240. (1区，IF:15.5)

11.Huang Z#, Zhuang Y#, Li W#, Ma M, Lei F, Qu Y, Li J, Luo H, Li C, Lu L, Ma L, Zhang X, Kou X, Jiang L, Mao X*, Shi S*. Apoptotic vesicles are required to repair DNA damage and suppress premature cellular senescence. J Extracell Vesicles. 2024 Apr;13(4): e12428. (1区，IF:15.5)

12.Lei F, Huang Z, Ou Q, Li J, Liu M, Ma L, Tan L, Lin Z*, Kou X*. Apoptotic vesicles rejuvenate mesenchymal stem cells via Rab7-mediated autolysosome formation and alleviate bone loss in aging mice. Nano Res. 2023;16, 822–833. (1区，IF: 9.6)

【社会兼职】

中华口腔医学会第八届儿童口腔医学专业委员会青年委员

【联系方式】

地址：广东省广东市陵园西路56号

邮箱：malan6@mail.sysu.edu.cn