夏娟 | 中山大学附属口腔医院

夏娟

教授博士生导师硕士生导师

导师简介

【学位 / 学历】

博士 / 博士研究生

【学术简历】

1993.09-1998.06 四川大学口腔医学专业获硕士学位

1998.09-2001.06 四川大学口腔医学专业获硕士学位

2001.09-2004.06 四川大学临床口腔医学专业获博士学位

【研究方向】

1.口腔黏膜病的发病机制、防治与康复新策略

2.口腔软硬组织缺损修复的新技术研发

【主持课题】

1. 2024-2027年：《放射诱导 POSTN+ 成纤维细胞活化扰动口腔黏膜细胞外基质稳态促进黏膜下纤维化的作用与机制研究》，国家自然科学基金区域创新发展联合基金重点支持项目，260万

2. 2022-2025年：《口腔角质形成细胞焦亡激活NF-κB-OPA1通路参与口腔扁平苔藓T细胞糖代谢重编程的机制研究》，国家自然科学基金面上项目，52万

3. 2019-2022年：《组蛋白乙酰化修饰调控miR-1181-SOX2轴在口腔白斑病发生发展中的作用及机制研究》，国家自然科学基金面上项目，57万

4. 2018-2021年：《Twist1调控上皮细胞可塑性在口腔黏膜癌前病变演进中的作用与防治研究》，广州市科技计划项目，100万

【发表论文】

1. Wang Y, Wang H, Cheng B, Xia J*. Associations between triglyceride glucose index-related obesity indices and anxiety: Insights from the National Health and Nutrition Examination Survey 2007-2012. J Affect Disord. 2025 Aug 1;382:443-452.

2. Wang Y, Wu Z, Zheng Y, Wang H, Cheng B, Xia J. Unraveling the genetic underpinnings of mitochondrial traits and associated circulating inflammatory proteins in Alzheimer's disease: Mitochondrial HtrA2-T cell CD5 negative axis. J Alzheimers Dis. 2025 May;105(2):505-518.

3. Jiang S, Ou L, Wang Y, Su K, Chen Z, He L, Xu X, Cheng B, Xia J, Fan Z. CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway. Int J Nanomedicine. 2025 Feb 5;20:1597-1613.

4. Zhang J#, Peng J#, Wang S, Wang L, Sun Y, Xia J, Cheng B, Hu Q*. Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition. Cell Death Discov. 2025 Jan 28;11(1):30.

5. Wu S, Yang S, Ou L, Zhang H, Wang L, Feng B, Bai Z, Li W, Cheng B, Toh WS, Xia J*. Melatonin-Loaded Hydrogel Modulates Circadian Rhythms and Alleviates Oxidative Stress and Inflammation to Promote Wound Healing. ACS Appl Bio Mater. 2025 Feb 17;8(2):1607-1620.

6. Zhang Y#, Ren J#, Shen Z#, Yang J, Yang J, Lin Z, Shi X, Zhao C, Xia J*. BMP2 peptide-modified polycaprolactone-collagen nanosheets for periodontal tissue regeneration. Front Bioeng Biotechnol. 2025 Mar 5;13:1523735.

7. Kuang S#, Yang J#, Shen Z, Xia J, Lin Z. Single-Cell and Spatial Multi-Omics Analysis Reveal That Targeting JAG1 in Epithelial Cells Reduces Periodontal Inflammation and Alveolar Bone Loss. Int J Mol Sci. 2024 Dec 10;25(24):13255.

8. Yang Z#, Deng M#, Ren L#, Fan Z, Yang S, Liu S, Ren X, Gao J, Cheng B, Xia J. Pyroptosis of oral keratinocyte contributes to energy metabolic reprogramming of T cells in oral lichen planus via OPA1-mediated mitochondrial fusion. Cell Death Discov. 2024 Sep 17;10(1):408.

9. Cai G#, Ren L#, Yu J, Jiang S, Liu G, Wu S, Cheng B, Li W, Xia J*. A Microenvironment-Responsive, Controlled Release Hydrogel Delivering Embelin to Promote Bone Repair of Periodontitis via Anti-Infection and Osteo-Immune Modulation. Adv Sci (Weinh). 2024 Sep;11(34):e2403786.

10. Wu S#, Yang T#, Ma M, Fan L, Ren L, Liu G, Wang Y, Cheng B, Xia J, Hao Z*. Extracellular vesicles meet mitochondria: Potential roles in regenerative medicine. Pharmacol Res. 2024 Aug;206:107307.

11. Guo J#, Su K#, Wang L#, Feng B#, You X, Deng M, Toh WS, Wu J, Cheng B, Xia J*. Poly(p-coumaric acid) nanoparticles alleviate temporomandibular joint osteoarthritis by inhibiting chondrocyte ferroptosis. Bioact Mater. 2024 Jun 12;40:212-226.

12. Wu R#, Chen Z#, Yu J#, Lai P, Chen X, Han A, Xu M, Fan Z, Cheng B, Jiang Y, Xia J. A graph-learning based model for automatic diagnosis of Sjögren's syndrome on digital pathological images: a multicentre cohort study. J Transl Med. 2024 Aug 8;22(1):748.

13. Xu X#, Pan X#, Fan Z, Xia J, Ren X. Lactate dehydrogenase B as a metabolism-related marker for immunotherapy in head and neck squamous cell carcinoma. Cell Signal. 2024 Aug;120:111200.

14. Li W#, Wu S#, Ren L, Feng B, Chen Z, Li Z, Cheng B, Xia J. Development of an Antiswelling Hydrogel System Incorporating M2-Exosomes and Photothermal Effect for Diabetic Wound Healing. ACS Nano. 2023 Nov 14;17(21):22106-22120.

15. Li Y, Ma Z, Li W, Xu X, Shen P, Zhang SE, Cheng B, Xia J. PDPN+ CAFs facilitate the motility of OSCC cells by inhibiting ferroptosis via transferring exosomal lncRNA FTX. Cell Death Dis. 2023 Nov 22;14(11):759.

16. Li W, Xu X, Ma Z, Shen P, Cheng B, Xia J, Li Y. LncRNA BANCR promotes oral squamous cell carcinoma progression via regulating Rab1A signaling. J Oral Pathol Med. 2023;52(8):727-737. doi:10.1111/jop.13463 (3.3)

17. Peng J#, Hu Q#, Wang C, Zhang J, Wang S, Wang L, Xia J, Cheng B. Depletion of Gr1+ myeloid cells attenuates high-fat-diet-aggravated esophageal squamous cell carcinoma in mice. Carcinogenesis. 2023;44(7):587-595. doi:10.1093/carcin/bgad047 (4.7）

18. Deng M#, Guo J#, Ling Z, Zhang C, He L, Fan Z, Cheng B, Xia J. KRAS mutations upregulate Runx1 to promote occurrence of head and neck squamous cell carcinoma. Mol Carcinog. 2023;62(9):1284-1294. doi:10.1002/mc.23563 (4.6)

19. Hao Z#, Liu G#, Ren L#, Liu J, Liu C, Yang T, Wu X, Zhang X, Yang L, Xia J, Li W*. A self-healing multifunctional hydrogel system accelerates diabetic wound healing through orchestrating immunoinflammatory microenvironment. ACS Appl Mater Interfaces. 2023 Apr 12. doi: 10.1021/acsami.2c23323. (9.5)

20. He L#, Guo J#, Fan Z, Yang S, Zhang C, Cheng B, Xia J. Exosomal miR-146b-5p derived from cancer-associated fibroblasts promotes progression of oral squamous cell carcinoma by downregulating HIPK3. Cell Signal. 2023;106:110635. doi: 10.1016/j.cellsig.2023.110635.

21. Hong Y, Wu J, Wu J, Xu H, Li X, Lin Z, Xia J*. Semi-Flipped Classroom-based Learning Interventions in a Traditional Curriculum of Oral Medicine: Students’ Perceptions and Teaching Achievements. BMC Med Educ. 2023 Jan 19;23(1):44. doi: 10.1186/s12909-023-04017-6.（3.2）

22. Li J#, Chen X#, Ren L, Chen X, Wu T, Wang Y, Ren X, Cheng B, Xia J. Type H vessel/platelet-derived growth factor receptor β+ perivascular cell disintegration is involved in vascular injury and bone loss in radiation-induced bone damage. Cell Prolif. 2023 Jan 24:e13406. doi: 10.1111/cpr.13406.（8.5）

23. Hao Z#, Ren L#, Zhang Z#, Yang Z, Wu S, Liu G, Cheng B, Wu J, Xia J*.A multifunctional neuromodulation platform utilizing Schwann cell-derived exosomes orchestrates bone microenvironment via immunomodulation, angiogenesis and osteogenesis. Bioact Mater. 2022 Nov 14;23:206-222. doi: 10.1016/j.bioactmat.2022.10.018. eCollection 2023 May （18.9）

24. Zhang Z#, Hao Z#, Xian C, Fang Y, Cheng B, Wu J, Xia J*. Neuro-bone tissue engineering: Multiple potential translational strategies between nerve and bone. Acta Biomater. 2022 Sep 16:S1742-7061(22)00585-2. doi: 10.1016/j.actbio.2022.09.023.（10.633）

25. Zhang C#, Ren L#, Zhang H, Yang S, Deng M, He L, Cao R, Zhao C, Xia J*. SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3. Hum Cell 2022 Jul;35(4):1100-1113.

26. Wu S#, Yang Z#, Wu T, Tao X, Hong Y, Cheng B, Xia J*. Application of online learning combined with case-based discussion in oral medicine education . J Dent Educ.2022 Apr 20. doi: 10.1002/jdd.12939. Online ahead of print.

27. Lin Y, Shi M, Xiang D, Zeng P, Gong Z, Liu H, Liu Q, Chen Z, Xia J, Chen Z. Construction of an end-to-end regression neural network for the determination of a quantitative index sagittal root inclination. J Periodontol. 2022 Feb 12. doi: 10.1002/JPER.21-0492. Online ahead of print.

28. Ling Z#, Li W#, Hu J#, Li Y, Deng M, Zhang S, Ren X, Wu T, Xia J, Cheng B, Tao X*. Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma. Cell Death Dis. 2022 Feb 17;13(2):158. doi: 10.1038/s41419-022-04610-5.

29. Cao R#, Zhang W#, Zhang H, Wang L, Chen X, Ren X, Cheng B, Xia J. Comprehensive analysis of the PRDXs family in head and neck squamous cell carcinoma. Front Oncol. 2022 Mar 8;12:798483. doi: 10.3389/fonc.2022.798483.

30. Cao R#, Cui L#, Zhang J, Ren X, Cheng B, Xia J. Immune-related lncRNA classification of head and neck squamous cell carcinoma. Cancer Cell Int. 2022 Jan 15;22(1):25. doi: 10.1186/s12935-022-02450-z.

31. Li W#, Jiang L#, Wu S, Yang S, Ren L, Cheng B, Xia J. A shape-programmable hierarchical fibrous membrane composite system to promote wound healing in diabetic patients. Small. 2022 Jan 17:e2107544. doi: 10.1002/smll.202107544.

32. Peng J#, Hu Q#, Chen X, Wang C, Zhang J, Ren X, Wang Y, Tao X, Li H, Song M, Cheng B, Wu T, Xia J*. Diet-induced obesity accelerates oral carcinogenesis by recruitment and functional enhancement of myeloid-derived suppressor cells. Cell Death Dis. 2021 Oct 14;12(10):946.

33. Wang Y#, Ren X#, Li W, Cao R, Liu S, Jiang L, Cheng B, Xia J. SPDEF suppresses head and neck squamous cell carcinoma progression by transcriptionally activating NR4A1. Int J Oral Sci. 2021 Oct 20;13(1):33.

34. Cao R, Liu S, Zhang J, Ren X, Chen X, Cheng B, Xia J. Integrative Analysis of TP53INP2 in Head and Neck Squamous Cell Carcinoma. Front Genet. 2021 Apr 9;12:630794. doi: 10.3389/fgene.2021.630794. eCollection 2021.

35. Wang Y#, Li Y#, Jiang L, Ren X, Cheng B, Xia J. Prognostic value of glycolysis markers in head and neck squamous cell carcinoma: a meta-analysis. Aging (Albany NY). 2021 Feb 26;13(5):7284-7299.

36. Li Y#, Wang Y#, Li J, Ling Z, Chen W, Zhang L, Hu Q, Wu T, Cheng B, Wang Y, Xia J*. Tacrolimus inhibits oral carcinogenesis through cell cycle control. Biomed Pharmacother. 2021 Jul;139: 111545.

37. Zhang C#, Wang H#, Deng M, He L, Ping F, He Y, Fan Z, Cheng B, Xia J. Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma. Int J Mol Med. 2021 Apr;47(4):1.

38. Chen X, Chen L, Tan J, Zhang L, Xia J, Cheng B, Zhang W*.Rspo1-LGR4 axis in BMSCs protects bone against radiation-induced injury through mTOR-dependent autophagy pathway. J Cell Physiol. 2021 Jun;236(6):4273-4289.

39. Fan Z#, He L#, Li M#, Cao R, Deng M, Ping F, Liang X, He Y, Wu T, Tao X, Xu J, Cheng B, Xia J. Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription. Neoplasia. 2020 Nov;22(11):617-629.

40. He Y#, Fan Z#, He L, Zhang C, Ping F, Deng M, Liu S, Wang Y, Cheng B, Xia J. Metformin combined with 4SC-202 inhibited the migration and invasion of OSCC via STAT3/Twist1. Onco Targets Ther. 2020 Oct 29;13:11019-11029.

41. Hu Q#, Peng J#, Jiang L, Li W, Su Q, Zhang J, Li H, Song M, Cheng B, Xia J, Wu T*. Metformin as a senostatic drug enhances the anticancer efﬁcacy of CDK4/6 inhibitor in head and neck squamous cell carcinoma . Cell Death Dis. 2020 Oct 28;11(10):925.

42. Ren L#, Chen X#, Chen X, Li J, Cheng B, Xia J. Mitochondrial Dynamics: Fission and fusion in fate determination of mesenchymal stem cells. Front Cell Dev Biol. 2020 Oct 15;8:580070.

43. Cao R#, Zhang J#, Jiang L, Wang Y, Ren X, Cheng B, Xia J. Comprehensive analysis of prognostic alternative splicing signatures in oral squamous cell carcinoma. Front oncol. 2020 Aug 28;10:1740.

44. He L#, Ping F#, Fan Z, Zhang C, Deng M, Cheng B, Xia J. Salivary exosomal miR-24-3p serves as a potential detective biomarker for oral squamous cell carcinoma screening. Biomed Pharmacother. 2020 Jan;121:109553.

【参编教材与论著】

1. 2024年副主编《口腔癌、口咽癌——全生命周期诊疗及康复》人民卫生出版社 9787117370981

2. 2025年副主编《口腔医学思政课与专业课融合案例集萃》人民卫生出版社

3. 2022年参编《口腔黏膜病学》（全国高等学校研究生规划教材，第二版）人民卫生出版社 9787117216791

4. 2022年参编《全国高级卫生专业技术资格考试指导口腔医学》人民卫生出版社 9787117318402

5. 2020年参编《口腔基础研究导论》人民卫生出版社 9787117293259

【获奖及学术荣誉】

1. 2021年广东省科学技术奖二等奖《分子标志物与口腔黏膜潜在恶性疾患的演变及诊疗》（第1完成人）

2. 2019年教育部科学技术进步奖二等奖《炎-癌转化调控网络在口腔黏膜潜在恶性疾患诊疗中的转化研究》（第2完成人）

【社会兼职】

1. 中华口腔医学会口腔医学科研管理分会副主任委员

2. 中国医院协会口腔医院分会副主任委员

3. 中国老年医学学会口腔医学分会副会长

4. 中华口腔医学会口腔黏膜病专委会常务委员

5. 广东省口腔医学会口腔黏膜病专委会主任委员

6. 广东省医师协会科研管理分会副主任委员

7. 广东省口腔医学会秘书长、常务理事

8. 广东省研究型医院学会监事长

9. 《中华口腔医学研究杂志（电子版）》副总编辑

【联系方式】

地址：广东省广州市越秀区陵园西路56号

邮箱：xiajuan@mail.sysu.edu.cn

【研究方向】

1.口腔黏膜病的发病机制、防治与康复新策略

2.口腔软硬组织缺损修复的新技术研发

【主持课题】

【发表论文】

1. Wang Y, Wang H, Cheng B, Xia J*. Associations between triglyceride glucose index-related obesity indices and anxiety: Insights from the National Health and Nutrition Examination Survey 2007-2012. J Affect Disord. 2025 Aug 1;382:443-452.

2. Wang Y, Wu Z, Zheng Y, Wang H, Cheng B*, Xia J*. Unraveling the genetic underpinnings of mitochondrial traits and associated circulating inflammatory proteins in Alzheimer's disease: Mitochondrial HtrA2-T cell CD5 negative axis. J Alzheimers Dis. 2025 May;105(2):505-518.

3. Jiang S, Ou L, Wang Y, Su K, Chen Z, He L, Xu X, Cheng B, Xia J*, Fan Z*. CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway. Int J Nanomedicine. 2025 Feb 5;20:1597-1613.

4. Zhang J#, Peng J#, Wang S, Wang L, Sun Y, Xia J*, Cheng B*, Hu Q*. Perilipin2-dependent lipid droplets accumulation promotes metastasis of oral squamous cell carcinoma via epithelial-mesenchymal transition. Cell Death Discov. 2025 Jan 28;11(1):30.

5. Wu S, Yang S, Ou L, Zhang H, Wang L, Feng B, Bai Z, Li W, Cheng B, Toh WS, Xia J*. Melatonin-Loaded Hydrogel Modulates Circadian Rhythms and Alleviates Oxidative Stress and Inflammation to Promote Wound Healing. ACS Appl Bio Mater. 2025 Feb 17;8(2):1607-1620.

6. Zhang Y#, Ren J#, Shen Z#, Yang J, Yang J, Lin Z, Shi X*, Zhao C*, Xia J*. BMP2 peptide-modified polycaprolactone-collagen nanosheets for periodontal tissue regeneration. Front Bioeng Biotechnol. 2025 Mar 5;13:1523735.

7. Kuang S#, Yang J#, Shen Z, Xia J*, Lin Z*. Single-Cell and Spatial Multi-Omics Analysis Reveal That Targeting JAG1 in Epithelial Cells Reduces Periodontal Inflammation and Alveolar Bone Loss. Int J Mol Sci. 2024 Dec 10;25(24):13255.

8. Yang Z#, Deng M#, Ren L#, Fan Z, Yang S, Liu S, Ren X, Gao J, Cheng B*, Xia J*. Pyroptosis of oral keratinocyte contributes to energy metabolic reprogramming of T cells in oral lichen planus via OPA1-mediated mitochondrial fusion. Cell Death Discov. 2024 Sep 17;10(1):408.

9. Cai G#, Ren L#, Yu J, Jiang S, Liu G, Wu S, Cheng B*, Li W*, Xia J*. A Microenvironment-Responsive, Controlled Release Hydrogel Delivering Embelin to Promote Bone Repair of Periodontitis via Anti-Infection and Osteo-Immune Modulation. Adv Sci (Weinh). 2024 Sep;11(34):e2403786.

10. Wu S#, Yang T#, Ma M, Fan L, Ren L, Liu G, Wang Y, Cheng B*, Xia J*, Hao Z*. Extracellular vesicles meet mitochondria: Potential roles in regenerative medicine. Pharmacol Res. 2024 Aug;206:107307.

11. Guo J#, Su K#, Wang L#, Feng B#, You X, Deng M, Toh WS, Wu J*, Cheng B*, Xia J*. Poly(p-coumaric acid) nanoparticles alleviate temporomandibular joint osteoarthritis by inhibiting chondrocyte ferroptosis. Bioact Mater. 2024 Jun 12;40:212-226.

12. Wu R#, Chen Z#, Yu J#, Lai P, Chen X, Han A, Xu M, Fan Z, Cheng B, Jiang Y*, Xia J*. A graph-learning based model for automatic diagnosis of Sjögren's syndrome on digital pathological images: a multicentre cohort study. J Transl Med. 2024 Aug 8;22(1):748.

13. Xu X#, Pan X#, Fan Z, Xia J*, Ren X*. Lactate dehydrogenase B as a metabolism-related marker for immunotherapy in head and neck squamous cell carcinoma. Cell Signal. 2024 Aug;120:111200.

14. Li W#, Wu S#, Ren L, Feng B, Chen Z, Li Z, Cheng B*, Xia J*. Development of an Antiswelling Hydrogel System Incorporating M2-Exosomes and Photothermal Effect for Diabetic Wound Healing. ACS Nano. 2023 Nov 14;17(21):22106-22120.

15. Li Y, Ma Z, Li W, Xu X, Shen P, Zhang SE, Cheng B*, Xia J*. PDPN+ CAFs facilitate the motility of OSCC cells by inhibiting ferroptosis via transferring exosomal lncRNA FTX. Cell Death Dis. 2023 Nov 22;14(11):759.

16. Li W, Xu X, Ma Z, Shen P, Cheng B, Xia J*, Li Y*. LncRNA BANCR promotes oral squamous cell carcinoma progression via regulating Rab1A signaling. J Oral Pathol Med. 2023;52(8):727-737. doi:10.1111/jop.13463 (3.3)

17. Peng J#, Hu Q#, Wang C, Zhang J, Wang S, Wang L, Xia J*, Cheng B*. Depletion of Gr1+ myeloid cells attenuates high-fat-diet-aggravated esophageal squamous cell carcinoma in mice. Carcinogenesis. 2023;44(7):587-595. doi:10.1093/carcin/bgad047 (4.7）

18. Deng M#, Guo J#, Ling Z, Zhang C, He L, Fan Z, Cheng B*, Xia J*. KRAS mutations upregulate Runx1 to promote occurrence of head and neck squamous cell carcinoma. Mol Carcinog. 2023;62(9):1284-1294. doi:10.1002/mc.23563 (4.6)

20. He L#, Guo J#, Fan Z, Yang S, Zhang C, Cheng B*, Xia J*. Exosomal miR-146b-5p derived from cancer-associated fibroblasts promotes progression of oral squamous cell carcinoma by downregulating HIPK3. Cell Signal. 2023;106:110635. doi: 10.1016/j.cellsig.2023.110635.

21. Hong Y, Wu J, Wu J, Xu H, Li X, Lin Z, Xia J*. Semi-Flipped Classroom-based Learning Interventions in a Traditional Curriculum of Oral Medicine: Students’ Perceptions and Teaching Achievements. BMC Med Educ. 2023 Jan 19;23(1):44. doi: 10.1186/s12909-023-04017-6.（3.2）

24. Zhang Z#, Hao Z#, Xian C, Fang Y, Cheng B*, Wu J*, Xia J*. Neuro-bone tissue engineering: Multiple potential translational strategies between nerve and bone. Acta Biomater. 2022 Sep 16:S1742-7061(22)00585-2. doi: 10.1016/j.actbio.2022.09.023.（10.633）

25. Zhang C#, Ren L#, Zhang H, Yang S, Deng M, He L, Cao R, Zhao C, Xia J*. SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3. Hum Cell 2022 Jul;35(4):1100-1113.

26. Wu S#, Yang Z#, Wu T, Tao X, Hong Y, Cheng B, Xia J*. Application of online learning combined with case-based discussion in oral medicine education . J Dent Educ.2022 Apr 20. doi: 10.1002/jdd.12939. Online ahead of print.

27. Lin Y, Shi M, Xiang D, Zeng P, Gong Z, Liu H, Liu Q, Chen Z, Xia J*, Chen Z*. Construction of an end-to-end regression neural network for the determination of a quantitative index sagittal root inclination. J Periodontol. 2022 Feb 12. doi: 10.1002/JPER.21-0492. Online ahead of print.

28. Ling Z#, Li W#, Hu J#, Li Y, Deng M, Zhang S, Ren X, Wu T, Xia J*, Cheng B*, Tao X*. Targeting CCL2-CCR4 axis suppress cell migration of head and neck squamous cell carcinoma. Cell Death Dis. 2022 Feb 17;13(2):158. doi: 10.1038/s41419-022-04610-5.

29. Cao R#, Zhang W#, Zhang H, Wang L, Chen X, Ren X, Cheng B*, Xia J*. Comprehensive analysis of the PRDXs family in head and neck squamous cell carcinoma. Front Oncol. 2022 Mar 8;12:798483. doi: 10.3389/fonc.2022.798483.

30. Cao R#, Cui L#, Zhang J, Ren X, Cheng B*, Xia J*. Immune-related lncRNA classification of head and neck squamous cell carcinoma. Cancer Cell Int. 2022 Jan 15;22(1):25. doi: 10.1186/s12935-022-02450-z.

31. Li W#, Jiang L#, Wu S, Yang S, Ren L, Cheng B*, Xia J*. A shape-programmable hierarchical fibrous membrane composite system to promote wound healing in diabetic patients. Small. 2022 Jan 17:e2107544. doi: 10.1002/smll.202107544.

32. Peng J#, Hu Q#, Chen X, Wang C, Zhang J, Ren X, Wang Y, Tao X, Li H, Song M, Cheng B*, Wu T*, Xia J*. Diet-induced obesity accelerates oral carcinogenesis by recruitment and functional enhancement of myeloid-derived suppressor cells. Cell Death Dis. 2021 Oct 14;12(10):946.

33. Wang Y#, Ren X#, Li W, Cao R, Liu S, Jiang L, Cheng B*, Xia J*. SPDEF suppresses head and neck squamous cell carcinoma progression by transcriptionally activating NR4A1. Int J Oral Sci. 2021 Oct 20;13(1):33.

34. Cao R, Liu S, Zhang J, Ren X, Chen X, Cheng B*, Xia J*. Integrative Analysis of TP53INP2 in Head and Neck Squamous Cell Carcinoma. Front Genet. 2021 Apr 9;12:630794. doi: 10.3389/fgene.2021.630794. eCollection 2021.

35. Wang Y#, Li Y#, Jiang L, Ren X, Cheng B*, Xia J*. Prognostic value of glycolysis markers in head and neck squamous cell carcinoma: a meta-analysis. Aging (Albany NY). 2021 Feb 26;13(5):7284-7299.

36. Li Y#, Wang Y#, Li J, Ling Z, Chen W, Zhang L, Hu Q, Wu T, Cheng B*, Wang Y*, Xia J*. Tacrolimus inhibits oral carcinogenesis through cell cycle control. Biomed Pharmacother. 2021 Jul;139: 111545.

37. Zhang C#, Wang H#, Deng M, He L, Ping F, He Y, Fan Z, Cheng B*, Xia J*. Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma. Int J Mol Med. 2021 Apr;47(4):1.

38. Chen X, Chen L, Tan J, Zhang L, Xia J*, Cheng B*, Zhang W*.Rspo1-LGR4 axis in BMSCs protects bone against radiation-induced injury through mTOR-dependent autophagy pathway. J Cell Physiol. 2021 Jun;236(6):4273-4289.

39. Fan Z#, He L#, Li M#, Cao R, Deng M, Ping F, Liang X, He Y, Wu T, Tao X, Xu J, Cheng B*, Xia J*. Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription. Neoplasia. 2020 Nov;22(11):617-629.

40. He Y#, Fan Z#, He L, Zhang C, Ping F, Deng M, Liu S, Wang Y, Cheng B*, Xia J*. Metformin combined with 4SC-202 inhibited the migration and invasion of OSCC via STAT3/Twist1. Onco Targets Ther. 2020 Oct 29;13:11019-11029.

41. Hu Q#, Peng J#, Jiang L, Li W, Su Q, Zhang J, Li H, Song M, Cheng B*, Xia J*, Wu T*. Metformin as a senostatic drug enhances the anticancer efﬁcacy of CDK4/6 inhibitor in head and neck squamous cell carcinoma . Cell Death Dis. 2020 Oct 28;11(10):925.

42. Ren L#, Chen X#, Chen X, Li J, Cheng B*, Xia J*. Mitochondrial Dynamics: Fission and fusion in fate determination of mesenchymal stem cells. Front Cell Dev Biol. 2020 Oct 15;8:580070.

43. Cao R#, Zhang J#, Jiang L, Wang Y, Ren X, Cheng B*, Xia J*. Comprehensive analysis of prognostic alternative splicing signatures in oral squamous cell carcinoma. Front oncol. 2020 Aug 28;10:1740.

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