【学位 / 学历】

博士 / 博士研究生

【学术简历】

1988.09-1993.06  中山医科大学口腔医学专业获学士学位

1995.09-1998.06  中山医科大学口腔医学专业获硕士学位

2002.02-2006.01  香港大学牙科材料学专业获博士学位

【研究方向】

1.口腔生物材料

2.口腔修复临床新技术/材料的研发与运用

3.人工智能在口腔修复的运用

【主持课题】

1. 2023.01.01- 2026.12.31：《牙周穿膜靶向抗菌促成骨复合药物控释体系的构建及其精准递送机制研究》，国家自然科学基金委员会，联合基金重点项目，255万

2. 2025.01.01-2028.12.31：《基于动-静转换电学微环境调控的功能化钛种植体表面构建及其抗菌成骨机制研究》，国家自然科学基金委员会，面上项目，49万

3. 2020.10.01-2024.09.30：《基于最弱链-仿生应力诱导理论的个性化功能梯度桩核修复系统研发》，广东省基础与应用基础研究基金委员会，区域联合基金重点项目，100万

4. 2021.01.01-2022.12.31：《3D打印压电水凝胶力-电响应微环境的构建及其对颌骨再生性修复的作用机制研究》，广东省科学技术厅，国际科技合作项目，50万

【发表论文】

1.Yanlan Wang#; Shiqi Zhou#; Xiaoshuang Wang; Dongheng Lu; Jinghong Yang ; Yu Lu; Xiaolei Fan; Changhao Li b*; Yan Wang*; Electroactive membranes enhance in-situ alveolar ridge preservation via spatiotemporal electrical modulation of cell motility. Biomaterials. 2025, 317.e123077.

2.Jiaojiao Yun; Ruihan Ge; James K.H. Tsoi; Yu Lu; Shuangzhuang Guo; Jiawen Guo*; Yan Wang*; Design and manufacturing of bio-inspired functionally graded ceramic-reinforced resin post-and-core restorations, Composites Part A: Applied Science and Manufacturing ,2025, 195.e108889.

3.Jiawen Guo#; Xiaolei Fan#; Yichen Yao; Jiaojiao Yun; Xiaoshuang Wang; Yanlan Wang; Yan Wang; Influence of Head Circumference on the Accuracy of Facial Scanning: An In vitro Study, Int Dent J, 2025, 75(2):898-907.

3.Tingting Zhang#; Jinghong Yang#; Yu Lu; Yanlan Wang; Xiaoshuang Wang; Yijiao Li; Weichang Li*; Yan Wang*; Synergistic Functions of the Janus Fibrous Membrane for Enhanced Bone Repair, ACS Appl Mater Interfaces, 2025, 17(10):14873-14887.

4.Shiqi Zhou#; Cairong Xiao#; Lei Fan#; Jinghong Yang; Ruihan Ge; Min Cai; Kaiting Yuan; Changhao Li; Ross William Crawford; Yin Xiao; Peng Yu; Chunlin Deng; Chengyun Ning*; Lei Zhou*; Yan Wang*; Injectable ultrasound-powered bone-adhesive nanocomposite hydrogel for electrically accelerated irregular bone defect healing, Journal of Nanobiotechnology, 2024, 22(1): 54-68.

5.Yichen Yao; Xin Wang; Lichieh Lin; Xiaolei Zhang; Wang Yan; ROR2-Related Skeletal Dysplasia Reveals Disrupted Chondrocyte Polarity through Modulation of BMP/TGF-β Signaling, Aging and Disease, 2024, 15(1): 282-292.

6.JiaoJiao. Yun#, M.F. Burrow, J.P. Matinlinna, H. Ding, S.M. Chan, J.K.H. Tsoi, Yan Wang*, Design of Multi-Functional Bio-Safe Dental Resin Composites with Mineralization and Anti-Biofilm Properties, J. Funct. Biomater. 15 (2024) 120-133.

7.Tingting Zhang#; Bo Yang#; Ruihan Ge; Chaobiao Zhang; Hui Zhang*; Yan Wang*; Effect of a Novel 'Scan Body' on the In Vitro Scanning Accuracy of Full-Arch Implant Impressions, Int Dent J, 2024. 74(4):847-854.

8.Jiawen Guo#; Yu Lu#; Runli Li#; Kai Zhou; Ruihan Ge; Diancai Zhao; Shasha Xia; Yan Wang*; Influence of repeated cut-off and rescanning on the trueness of the intraoral digital scans. J Dent, 2024, 150.e105153.

9.Changhao Li; Siyu Zhang; Yichen Yao; Yanlan Wang; Cairong Xiao; Bo Yang; Jingyan Huang; Weichang Li; Chengyun Ning; Jinxia Zhai*; Peng Yu*; and Yan Wang*; Piezoelectric Bioactive Glasses Composite Promotes Angiogenesis by the Synergistic Effect of Wireless Electrical Stimulation and Active Ions, Adv Healthc Mater, 2023, 12(17). e2300064.

10.Jinghong Yang; Kaiting Yuan; Tingting Zhang; Shiqi Zhou; Weichang Li*; Zetao Chen*; Yan Wang*; Accelerated Bone Reconstruction by the Yoda1 Bilayer Membrane via Promotion of Osteointegration and Angiogenesis, Advanced Healthcare Materials, 2023, 12(18):17.e202203105.

11.Peina Huang#; Jieyun Xu#; Lv Xie#; Guangqi Gao; Shoucheng Chen; Zhuohong Gong;  Xiaomei Lao; Zhengjie Shan; Jiamin Shi; Zhaocai Zhou; Zhuofan Chen; Yang Cao*; Yan Wang*; Zetao Chen*; Improving hard metal implant and soft tissue integration by modulating the “inflammatory-fibrous complex” response, Bioactive Mater, 2023(20):42-52.

12.Cairong Xiao#; Lei Fan#; Shiqi Zhou#; Xinchang Kang; Pengfei Guan; Rumin Fu; Changhao Li; Jian Ren; Zhengao Wang; Peng Yu; Yan Wang*; Chunlin Deng*; Lei Zhou*; Chengyun Ning*; OneDimensional Ferroelectric Nanoarrays with Wireless Switchable Static and Dynamic Electrical Stimulation for Selective Regulating Osteogenesis and Antiosteosarcoma, ACS Nano, 2022, 16(12): 20770-20785.

13.Min Cai#; Xiaojun Li#; Meng Xu; Shiqi Zhou; Lei Fan; Jingyan Huang; Cairong Xiao; Yichen Lee; Bo Yang; Le Wang; Ross William Crawford; Yin Xiao; Lei Zhou*; Chengyun Ning*; Yan Wang*; Injectable Tumor Microenvironment-Modulated Hydrogels with Enhanced Chemosensitivity and Osteogenesis for Tumor-Associated Bone Defects Closed-Loop Management, Chemical Engineering Journal, 2022, 450.e138086.

14.Lee Y, Huang J, Bing Z, Yuan K, Yang J, Cai M, Zhou S, Yang B, Teng W, Li WC, Wang Y*. pH-responsive cinnamaldehyde-TiO2 nanotube coating: fabrication and functions in a simulated diabetes condition. J Mater Sci Mater Med. 2022 Sep 5;33(9):63. doi: 10.1007/s10856-022-06683-2

15.Bo Yang, Wondwosen A Aregawi, Ruoqiong Chen, Lin Zhang, Yan Wang*, Alex Siu Lun Fok*. Accelerated fatigue model for predicting composite restoration failure. Journal of Dental Research, 2022.12, 101(13):1606-1612

16.Bo Yang*, Xuefei Pang*, Zhipeng Li*, Zhuofan Chen#, Yan Wang#.  Immuonodulation in the treatment of peridontitis: Progress and Perspectives (Review). Frontiers in Immunology. 2021.11.19 :1664-3224, 11.19, 12:781378

17.Taghrid Twittera*, Jiajun Yang*, Jiawen Guo, Hui Zhang*, Yan Wang*.  Ion release and biocompatibility of Co-Cr alloy fabricated by selective laser melting from recycled Co-Cr powder:    J Prosthet Dent 2021 Nov.12:S0022-3913(21):00491-1

18.Jingyan Huang#, Ruoqi Li#, Jinghong Yang, Min Cai, Yizhen Li, Anxun Wang, Bin Cheng, Yan Wang*. Bioadaptation of Implants to in-vitro and in-vivo Oxidative Stress Pathological Conditions via Nanotopography-induced FoxO1 Signaling Pathways to Enhance Ostoimmunal Regeneration. Bioactive Mater. 2021, 6 (10): 3164-3176.  (IF 14.593)

19.Taghrid Aldhohrah, Mubarak Mashrah, Yan Wang*. Effect of 2-implant mandibular over denture with different attachments and loading protocols on peri-implant health and prosthetic complications: A systematic review and network meta- analysis. J Prosthet Dent. 2021, S0022-3913(20)30806-4.

20.Sin Man Chan, Jiawen Guo, Wondwosen A Aregawi, Jiajun Yang, Alex Fok, Yan Wang*. Investigation of Mechanical Performances and Polymerization Shrinkage of Dual-Cured Resin Cements as Core Build-Up Material.  Dent Mater J  2021:40（5）: 1217-1225 (IF 2.102)

【参编教材与论著】

1. 2024年 副主编《口腔修复辞典》 人民卫生出版社

2. 2020年 编委《口腔基础研究导论》 人民卫生出版社 9787117293259

【获奖及学术荣誉】

1. 2024年 广东省医院协会医院管理与科技创新奖（排名第一），一等奖，省级

2. 2023年 广东医学科技奖（排名第一），二等奖，省级

3. 2021年 广东省本科高校课程思政优秀案例（排名第二），省级

4. 2023年 中山大学第十届本科教育教学成果奖（排名第四），二等奖，校级

【社会兼职】

1. 香港大学名誉教授

2. 中华口腔医学会口腔修复学专业委员会副主任委员

3. 中华口腔医学会口腔材料专业委员会常务委员

4. 广东省口腔医学会副会长

5. 广东省口腔医学会口腔修复学专业委员会主任委员

6. 《中华口腔医学研究杂志（电子版）》执行副主编

7. 《Dental Materials》编委

8. 《口腔疾病防治》编委

【联系方式】

地址：广州市越秀区大东街道陵园西路56号

电话：020-83802805

邮箱：wangyan9@mail.sysu.edu.cn